Reprogramming cells to evade tumor suppression
Multiplex-edited. AI-guided. Built for tough tumors.
Our Science
Why most cell therapies fail
The tumor microenvironment (TME) suppresses immune cells and blocks durable function.
How we fix it
We reprogram cells to evade suppressive signals like TGFβ and PD-1—preserving potency, even in the most hostile tumors.
The result
Resilient cell therapies, built for solid and blood cancers.
What sets our therapies apart
Multiplex
Precision
Many edits, one step—designed for synergy, built for simplicity
Off-the-Shelf Chassis
Donor-derived cells cut costs, shorten treatment timelines, and expand access
Intrinsic
Resilience
Edits block suppression, preserving function and extending responses
The KiraLOGIC Platform
Why smarter edits matter
Most models rely on static readouts. We learn from real function.
How our platform works
KiraLOGIC predicts optimal multiplex edits using suppression data in a closed-loop system.
The result
Less wet lab burden, faster iteration, and more durable therapies.
How KiraLOGIC accelerates discovery
Predictive Intelligence
Models immune function using suppression-based readouts
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Combinatorial Exploration
Screens billions of edits to find synergistic combinations
Transferable Learning
Every program improves design speed across T, NK, and γδ cells
​Smarter design. Faster programs. Better outcomes.​
Our Support
Our Recognitions
Nucleate Activator Program
Finalists in the 2024 Nucleate Activator Program final pitch showcase in Boston
HUCP Innovation Fund x CBE Ventures Competition
HUCP Innovation Fund x CBE Ventures Competition
Finalists in the 2023 Harvard Undergraduate Capital Partners Innovation Fund x Consulting, Bus., & Environment Venture Comp
Presidents Innovation Challenge
Semi-finalists in the 2024 Harvard iLab's President's Innovation Challenge
Co-founder and CEO, Aaron Edwards selected to be a Termeer Fellow, a values-driven leadership program for first time biotech founder/CEOs
Finalists in the 2024 M2D2 $200k Grand Challenge
Co-founder and CSO, Ryan Murray selected to be in 5050 Program, helping foster deep tech scientists/engineers become great founders.
